145165-95-3Relevant articles and documents
Stereospecific Intramolecular Arylation of 2- and 3-Pyridyl Substituted Alkylamines via Configurationally Stable α-Pyridyl Organolithiums
Maury, Julien,Zawodny, Wojciech,Clayden, Jonathan
supporting information, p. 472 - 475 (2017/02/10)
Treatment of N′-aryl urea derivatives of enantiomerically enriched α-(2-pyridyl) and α-(3-pyridyl)alkylamines with a base leads to the migration of the N′-aryl substituent from N to C in a nonclassical' intramolecular nucleophilic aromatic substitution re
Addition of allylmetal reagents to the imine derived from 2-pyridine carboxaldehyde and methyl (S)-valinate. Synthesis of (S)- and (R)-1-(2-pyridyl)-3-butenamine
Alvaro, Giuseppe,Savoia, Diego
, p. 2083 - 2092 (2007/10/03)
Allylmetal reagents add to the imine derived from 2-pyridine carboxaldehyde and methyl (S)-valinate or to preformed imine-metal salt complexes to give mainly the S,S- or the R,S-secondary homoallylic amine, depending on the nature of the allylmetal reagents. Both the (S)- and (R)-1-(2-pyridyl)-3-butenamine were prepared with high enantiomeric purity by removal of the auxiliary group.