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145166-04-7

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145166-04-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 145166-04-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,6 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 145166-04:
(8*1)+(7*4)+(6*5)+(5*1)+(4*6)+(3*6)+(2*0)+(1*4)=117
117 % 10 = 7
So 145166-04-7 is a valid CAS Registry Number.

145166-04-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (+/-)-trans-2-aminocycloheptanol

1.2 Other means of identification

Product number -
Other names trans-2-aminocycloheptanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145166-04-7 SDS

145166-04-7Relevant articles and documents

Lipase-catalyzed Kinetic Resolution of (+/-)-trans- and cis-2-Azidocycloalkanols

Ami, Ei'ichi,Ohrui, Hiroshi

, p. 2150 - 2156 (2007/10/03)

The lipase-catalyzed kinetic resolution of trans- and cis-2-azidocycloalkanols and the preparation of enantiomerically pure trans- and cis-2-aminocycloalkanols are described. Four kinds of lipases were screened for the acetylation of trans- and cis-2-azidocycloalkanols. Among them, Pseudomonas sp. lipases (lipase PS and lipase AK, Amamo Pharmaceutical Co.) showed the highest enantioselectivity. These products were converted to the corresponding 2-aminocycloalkanols to determine their enantiomeric excess (ee) and absolute configurations by HPLC and CD analyses, using (S)-TBMB carboxylic acid [(S)-2-tert-butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid] as the chiral conversion reagent. The results of the CD analysis proved N,O-bis-(S)-TBMB carboxylated cis-2-aminocycloalkanols to adopt a predominantly N-equatorial conformation. The partially resolved trans- and cis-2-aminocycloalkanols, except for trans-2-aminocyclopentanol, were recrystallized from ethyl acetate to give enantiomerically pure forms.

CYCLOALKYL AMINE BIS-ARYL SQUALENE SYNTHASE INHIBITORS

-

, (2008/06/13)

This invention relates to a class of novel polycyclic compounds containing a cycloalkyl ring having substituted there on a primary amine and which is further linked or bridged to two mono- and/or bicyclic rings and which reduces levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention

Compounds with Bridgehead Nitrogen. Part 43. The Reaction between trans-2-Aminocycloalkanethiols and Formaldehyde

Barkworth, Peter M. R.,Crabb, Trevor A.

, p. 2777 - 2782 (2007/10/02)

trans-2-Aminocyclopentanethiol condenses with formaldehyde to give rel-(3aR,6aR,9aR,12aR)-6,12-methanoperhydrodicyclopentanodithiadiazecine, whereas trans-2-aminocyclohexanethiol and trans-2-aminocycloheptanethiol give 1:1 mixture of diastereomeric bis(perhydrocycloalkanothiazol-3-yl)methanes.

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