1451729-34-2Relevant academic research and scientific papers
L-Proline-catalyzed three-component domino reactions in the regioselective synthesis of novel densely functionalized pyrazolo[3,4-b]pyridines
Gunasekaran, Pethaiah,Indumathi, Sethuraman,Perumal, Subbu
, p. 8318 - 8325 (2013)
The l-proline-catalyzed three-component synthesis of novel 3-methyl-1-aryl-1H-pyrazolo[3,4-b]pyridines in good yields from the reaction of 3-methyl-1-aryl-1H-pyrazol-5-amines, 1,3-dicarbonyl compounds and aromatic aldehydes in ethanol is described. This domino transformation presumably involves the formation of two C-C bonds and one C-N bond in a single synthetic operation.
