1451735-27-5

Upstream product

• 1447715-66-3 2-(1-chloroethyl)-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine 
• 13134-38-8 3,6-dimethylpyrazin-2-yl amine 
• 1451735-35-5 5,8-dimethyl-2-[(E)-1-methyl-2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-vinyl][1,2,4]triazolo[1,5a]pyrazine 

Relevant academic research and scientific papers

IMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS

This invention is directed to compounds (I), which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula. The present invention further provides a compound of formula (I) for use in treating a subject suffering from a neurodegenerative disorder, a drug addiction or a psychiatric disorder (formula I), wherein HET is a heteroaromatic group of formula II containing from 2 to 4 nitrogen atoms: (formula II).