145174-86-3Relevant academic research and scientific papers
Synthesis of α,α-Disubstituted α-Amino Acid Amides by Phase-Transfer Catalyzed Alkylation
Kaptein, Bernard,Boesten, Wilhelmus H. J.,Broxterman, Quirinus B.,Schoemaker, Hans E.,Kamphuis, Johan
, p. 6007 - 6010 (2007/10/02)
α,α-Disubstituted α-amino acid amides were prepared in 17-88 percent chemical yield by the phase-transfer catalyzed alkylation of N-benzylidene α-H amino acid amides, followed by weak acidic hydrolysis of the Schiff bases.
