145175-81-1Relevant academic research and scientific papers
Apparent proton-catalyzed Meerwein-Ponndorf-Verley type reduction of 8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazep ine
Ramig,Kuzemko,Parrish,Carpenter
, p. 6279 - 6282 (1992)
When treated with 2-propanol in the presence of HCl, reduction of the C4-N double bond in 8 chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin e occurs. Data are presented which indicate 2-propanol is the reductant in a two-step mechanism.
