145178-01-4Relevant academic research and scientific papers
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents
Romagnoli, Romeo,Baraldi, Pier Giovanni,Lopez-Cara, Carlota,Preti, Delia,Aghazadeh Tabrizi, Mojgan,Balzarini, Jan,Bassetto, Marcella,Brancale, Andrea,Fu, Xian-Hua,Gao, Yang,Li, Jun,Zhang, Su-Zhan,Hamel, Ernest,Bortolozzi, Roberta,Basso, Giuseppe,Viola, Giampietro
, p. 9296 - 9309 (2013)
The biological importance of microtubules make them an interesting target for the synthesis of antitumor agents. The 2-(3′,4′,5′- trimethoxybenzoyl)-5-aminobenzo[b]thiophene moiety was identified as a novel scaffold for the preparation of potent inhibitor
Divergent Synthesis of Disulfanes and Benzenesulfonothioates Bearing 2-Aminofurans From N-Tosylhydrazone-Bearing Thiocarbamates
Mai, Shaoyu,Song, Qiuling
supporting information, p. 7952 - 7957 (2017/06/27)
An efficient and convenient synthesis of valuable disulfanes and benzenesulfonothioates, having a 2-aminofuran framework, has been developed by employing a copper-catalyzed transformation of readily available N-tosylhydrazone-bearing thiocarbamates. This method features an inexpensive metal catalyst, mild reaction conditions, good functional-group tolerance, short reaction times, and delivers valuable and complex products. A copper carbene generated from an N-tosylhydrazone-bearing thiocarbamate is proposed as the key intermediate for the transformation and it triggers the subsequent cascade. Remarkably, the Ts anion released from N-tosylhydrazone further serves as a nucleophile, thus rendering the formation of benzenesulfonothioates under controlled conditions.
Light-triggered self-assembly of gold nanoparticles based on photoisomerization of spirothiopyran
Shiraishi, Yasuhiro,Tanaka, Kazuya,Shirakawa, Eri,Sugano, Yoshitsune,Ichikawa, Satoshi,Tanaka, Shunsuke,Hirai, Takayuki
supporting information, p. 8304 - 8308 (2013/09/02)
Give it some stick: UV irradiation of spirothiopyran in an aqueous solution of gold nanoparticles (AuNPs) gives AuNP aggregates. The aggregate size is tuned by the photoirradiation time and the aggregation is facilitated by the covalent binding of photois
