145192-01-4Relevant academic research and scientific papers
Antifungal agents. 1. Synthesis and antifungal activities of estrogen-like imidazole and triazole derivatives
Massa,Di Santo,Retico,Artico,Simonetti,Fabrizi,Lamba
, p. 495 - 502 (2007/10/02)
The synthesis of some 2-aryl-1-(4-methoxyphenyl)-1-(1H-imidazol-1-yl)ethane derivatives and related 1H-1,2,4- and 1H-1,3,4-triazoles is described. The molecular structure of new derivatives has been established by 1H NMR spectra and X-ray crystallographic analysis. When tested in solid agar cultures the azole derivatives showed from moderate to potent in vitro antifungal activity against Candida albicans and Candida spp.
