145194-59-8Relevant academic research and scientific papers
Synthesis and biological evaluation of halogenated e-stilbenols as promising antiaging agents
Amoroso, Rosa,Balaha, Marwa,De Filippis, Barbara,Di Filippo, Ester Sara,Ferrone, Vincenzo,Fulle, Stefania,Giampietro, Letizia,Locatelli, Marcello,Pietrangelo, Tiziana,Tartaglia, Angela
, (2020)
The increased risk of illness and disability is related to the age inevitable biological changes. Oxidative stress is a proposed mechanism for many age-related diseases. The crucial importance of polyphenol pharmacophore for aging process is largely descr
PPARα agonists based on stilbene and its bioisosteres: Biological evaluation and docking studies
De Filippis, Barbara,Agamennone, Mariangela,Ammazzalorso, Alessandra,Bruno, Isabella,D'Angelo, Alessandra,Di Matteo, Mauro,Fantacuzzi, Marialuigia,Giampietro, Letizia,Giancristofaro, Antonella,MacCallini, Cristina,Amoroso, Rosa
supporting information, p. 1513 - 1517 (2015/08/18)
A new series of gemfibrozil analogues conjugated with trans-stilbene were synthesized and evaluated with the aim of developing new PPARα agonists. The phenyls of stilbene were modified by introducing substituents in the ortho or para position and only the
Synthesis and anti-implantation activity of new stilbene derivatives
Bandichhor, Rakeshwar,Singh, Kunwar A.,Nosse, Bernd,Tandon, Vishnu K.
, p. 452 - 455 (2007/10/03)
New stilbene (CAS 56-53-1) derivatives have been synthesized by reductive elimination of desosybenzoin analogs which were obtained by Fries rearrangement of the corresponding phenolic esters. The chemical structures of the compounds obtained were confirmed by 1H-NMR, IR and elemental analysis. Anti-implantation activity of the compounds was determined by performing experiments with adult male and female Spargue-Dawley rats of proven fertility. A 67 % inhibition of implantation was observed separately with compounds 3f and 3i.
A convenient one-pot completely stereoselective synthesis of trans-4-Hydroxystilbenes and its derivatives and X-ray structure of its precursor
Chhor, Rakeshwar B.,Singh, Kunwar A.,Nosse,Tandon, Vishnu K.
, p. 2519 - 2530 (2007/10/03)
The synthesis of E-isomer of 4-Hydroxystilbene and its derivatives 3 by reductive elimination of the carbonyl function in 2-phenyl-1-(4-hydroxyphenyl)ethan-1-one and its derivatives 2 and the X-ray structure of 2a are described.
