1451992-80-5

Upstream product

• 331625-80-0 (2S,3R,4R)-2,3,5-tris(4-methoxybenzyloxy)-1,4-pentanediol 
• 10387-40-3 potassium thioacetate 

Downstream Products

• 1451992-81-6 (3R,4S,5R)-4,5-bis-p-methoxybenzyloxy-3-p-methoxybenzyloxymethyl-1,2-dithiane 

Relevant academic research and scientific papers

Synthesis of a novel 1,2-dithianenucleoside via Pummerer-like reaction, followed by Vorbruggen glycosylation between a 1,2-dithiane derivative and uracil

The novel 1,2-dithianenucleoside was designed as a hybrid type of modification between 4′-thioribonucleoside and altritol nucleoside. The desired compound, i.e., 1-[(3R,4R,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-1,2- dithianyl]uracil (20), was prepared via the Pummerer-like reaction, followed by Vorbruggen glycosylation between an appropriately protected 1,2-dithiane derivative and silylated uracil.