145212-53-9Relevant academic research and scientific papers
Asymmetric [2 + 2] cycloaddition reaction catalyzed by a chiral titanium reagent
Narasaka, Koichi,Hayashi, Yujiro,Shimadzu, Hideshi,Niihata, Shigeo
, p. 8869 - 8885 (2007/10/02)
In the presence of certain Lewis acids, alkenes containing an alkylthio group (for example, ketene dithioacetals, alkenyl sulfides, alkynyl sulfides, and allenyl sulfides) react with electron deficient olefins to give the corresponding cyclobutane, cyclobutene, or methylene cyclobutane derivatives. By employing a chiral titanium catalyst generated in situ from dichlorodiisopropoxytitanium and a tartrate-derived chiral diol, the [2 + 2] cycloaddition reaction proceeds with high enantioselectivity.
Cycloaddition Reaction between Allenyl Sulfides and Electron Deficient Olefins Promoted by Lewis Acids
Hayashi, Yujiro,Niihata, Shigeo,Narasaka, Koichi
, p. 2091 - 2094 (2007/10/02)
Methylenecyclobutane derivatives are prepared by the Lewis acid promoted cycloaddition reactions of 1-substituted-1-methylthio-1,2-propadienes and electron deficient olefins.The asymmetric cycloaddition of the allenyl sulfides also proceeds in
