1452161-84-0Relevant articles and documents
Domino Rh-catalyzed hydroformylation-double cyclization of o-amino cinnamyl derivatives: Applications to the formal total syntheses of physostigmine and physovenine
Chiou, Wen-Hua,Kao, Chien-Lun,Tsai, Jui-Chi,Chang, Yun-Man
, p. 8232 - 8234 (2013/09/12)
A parallel, versatile and efficient route to synthesis of pyrrolidinoindoline and tetrahydrofuranoindoline alkaloids from cinnamyl derivatives has been developed, featuring a domino Rh-catalyzed hydroformylation-double cyclization sequence. This method can be applied to the syntheses of anti-Alzheimer drugs such as physostigmine and physovenine.