145232-39-9

Upstream product

• 84890-97-1 (S)-3-tert-Butoxycarbonylamino-4-isobutoxycarbonyloxy-4-oxo-butyric acid benzyl ester 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 7536-58-5 BOC-L-aspartic acid 4-benzyl ester 
• 13798-75-9 N^α-t-butoxycarbonylaspartic acid α-N-hydroxysuccinimide ester β-benzyl ester 

Downstream Products

• 1167435-33-7 C₃₁H₃₆N₂O₈ 
• 1318780-39-0 C₃₁H₃₉N₃O₁₀ 
• 1318780-41-4 C₃₂H₄₁N₃O₁₀ 
• 1318780-43-6 C₃₀H₃₉N₃O₈S 

Relevant academic research and scientific papers

Synthesis and biological activity of novel L-amino acid based analgesic compounds

Synthesis and analgesic activity studies of a series of L-amino acid based compounds were described. These compounds were designed as potential N-type Calcium Channel Blockers and their structures were confirmed by 1H NMR and ESI-MS spectra. Some of the compounds exhibited significant analgesic activity in Mouse Hot-Plate tests. According to the data of pharmacological experiments, we carried out preliminary structure-activity studies and the results indicated that this kind of compounds was useful for the development of new analgesic drugs.

Development of peptide 3D structure mimetics: Rational design of novel peptoid cholecystokinin receptor antagonists

The two hormones cholecystokinin and gastrin share the same C-terminal sequence of amino acids, namely Gly29-Trp30-Met31-Asp32-Phe33-NH2. Nevertheless, this congruence has not precluded usi