1452392-32-3

Basic information

• Product Name: C₂₇H₂₀FN₃O₃S
• Synonyms: C₂₇H₂₀FN₃O₃S
• CAS NO: 1452392-32-3
• Molecular Weight: 485.539
• Mol File: 1452392-32-3.mol

Chemical Properties

• CAS DataBase Reference: C₂₇H₂₀FN₃O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₂₀FN₃O₃S(1452392-32-3)
• EPA Substance Registry System: C₂₇H₂₀FN₃O₃S(1452392-32-3)

Safety Data

• Hazardous Substances Data: 1452392-32-3(Hazardous Substances Data)

Upstream product

• 1287715-28-9 3-isothiocyanato-1-methylindolin-2-one 
• 139715-34-7 1-methyl-3-(2-(4-fluorophenyl)-2-oxoethylidene)indolin-2-one 

Relevant articles and documents

Highly efficient enantioselective construction of bispirooxindoles containing three stereocenters through an organocatalytic cascade michael-cyclization reaction

Bispirooxindole derivatives containing three stereocenters, including two spiro quaternary centers, were synthesized in a high-yielding, atypically rapid, and stereocontrolled cascade Michael-cyclization reaction between methyleneindolinones and isothiocyanato oxindoles catalyzed by a bi- or multifunctional organocatalyst. Mild conditions were used to construct bispirooxindoles with excellent enantio- and diastereomeric purities within less than 1 min. Catalyst reconfiguration offered access to the opposite enantiomer. This exceptionally highly efficient procedure will allow diversity-oriented syntheses of this intriguing class of compounds with potential biological activities. Copyright