139715-34-7

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 91-56-5 indole-2,3-dione 
• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 139715-33-6 1-methyl-3-hydroxy-3-(2-(4-fluorophenyl)-2-oxoethyl)indolin-2-one 

Downstream Products

• 1400564-59-1 C₂₃H₁₄FNO₂ 
• 1452392-32-3 C₂₇H₂₀FN₃O₃S 
• 1374031-06-7 N-[(Z)-1-(4-fluorophenyl)-2-(1-methyl-2-oxoindolin-3-ylidene)ethylidene]-4-methylbenzenesulfonamide 
• 139715-35-8 2',4'-dihydro-5'-(4-fluorophenyl)-1-methyl-2'-phenylspiro<3H-indol-3,3'-(3H)pyrazol>-2(1H)-one 
• 134277-24-0 C₁₇H₁₄FN₃O 

Relevant academic research and scientific papers

3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: Potential candidates for chemoprevention

Induction of cytoprotective phase 2 enzymes through inhibition of Keap1, a repressor of transcription factor Nrf2, is a cancer-prevention strategy. Compounds that elicit antiinflammatory and cytoprotective effects are promising candidates for chemoprevent

Investigation on the reactions of fluorine containing 1,3-dihydro-3-(2-phenyl-2-oxoethylidene)-2H-indol-2-ones with hydrazine derivatives

Reactions of fluorine containing 1,3-dihydro-3-(2-phenyl-2-oxoethylidene)-2H-indol-2-ones (II) with various hydrazines have been studied in different media.Reaction of II with hydrazine hydrate in abs. ethanol gives 2',4'-dihydro-5'-phenylspiro3H-indole-