145255-19-2

Basic information

• Product Name: 5-Aminopyridine-2-carboxamide
• Synonyms: 5-Aminopyridine-2-carboxamide;2-Pyridinecarboxamide,5-amino-(9CI);5-AMINOPYRIDINE-2-CARBOXAMIDE,PURITY:95% MIN(HPLC);5-AMino-2-pyridine carboxaMide;5-AMinopicolinaMide
• CAS NO: 145255-19-2
• Molecular Formula: C₆H₇N₃O
• Molecular Weight: 137.13928
• EINECS: 1312995-182-4
• Product Categories: AMIDE;PYRIDINE
• Mol File: 145255-19-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 427.311 °C at 760 mmHg
• Flash Point: 212.23 °C
• Appearance: /
• Density: 1.323 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 5-Aminopyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Aminopyridine-2-carboxamide(145255-19-2)
• EPA Substance Registry System: 5-Aminopyridine-2-carboxamide(145255-19-2)

Safety Data

• Hazardous Substances Data: 145255-19-2(Hazardous Substances Data)

Usage

Uses

5-Aminopyridine-2-carboxamide is a synthetic building block used as a reactant in the discovery of carboline analogs as potent MAPKAP-K2 inhibitors.

InChI:InChI=1/C6H7N3O/c7-4-1-2-5(6(8)10)9-3-4/h1-3H,7H2,(H2,8,10)

Upstream product

• 30651-24-2 5-nitropicolinic acid 
• 59290-34-5 5-nitropyridine-2-carboxamide 
• 24242-20-4 5-amino-pyridine-2-carboxylic acid 
• 100367-55-3 5-nitropyridine-2-carbonitrile 
• 4487-59-6 2-bromo-5-nitropyridine 
• 55338-73-3 5-amino-2-cyanopyridine 

Relevant articles and documents

SUBSTITUTED OXOPYRIDINE DERIVATIVES

The invention relates to substituted oxopyridine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents

The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.

[1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS

Novel [1,2,4]triazolo[1,5-a]pyridine compounds are disclosed that have a Formula represented by the following: (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, joint disease, inflammation, and others.