145255-87-4

Upstream product

• 626-35-7 nitroacetic acid ethyl ester 
• 145255-80-7 4-(2,4-Dioxo-4H-pyrido[2,3-d][1,3]oxazin-1-yl)-benzoic acid ethyl ester 

Downstream Products

• 145435-34-3 4-(4-Amino-3-nitro-2-oxo-2H-[1,8]naphthyridin-1-yl)-benzoic acid ethyl ester 
• 1027975-12-7 4-(3,4-Diamino-2-oxo-2H-[1,8]naphthyridin-1-yl)-benzoic acid ethyl ester 
• 1025909-29-8 4-(4-Chloro-3-nitro-2-oxo-2H-[1,8]naphthyridin-1-yl)-benzoic acid ethyl ester 

Relevant academic research and scientific papers

New Bronchodilators. 3. Imidazonaphthyridin-4(5H)-ones

In order to develop new oral bronchodilators, a series of novel imidazonaphthyridin-4(5H)-ones 5 were designed and synthesized.Some of these new heterocycles exhibited more potent bronchodilator activity in vitro and in vivo than theophylline.