New Bronchodilators. 3. Imidazonaphthyridin-4(5H)-ones

DOI: 10.1021/jm00104a013

Source and publish data:

Journal of Medicinal Chemistry p. 4866 - 4874 (1992)

Update date:2022-08-05

Topics:

Authors:

Suzuki, Fumio

Kuroda, Takeshi

Kawakita, Takashi

Manabe, Haruhiko

Kitamura, Shigeto

et al. et al.

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Article abstract of DOI:10.1021/jm00104a013

In order to develop new oral bronchodilators, a series of novel imidazo<4,5-c><1,8>naphthyridin-4(5H)-ones 5 were designed and synthesized.Some of these new heterocycles exhibited more potent bronchodilator activity in vitro and in vivo than theophylline.

Full text of DOI:10.1021/jm00104a013

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