1452572-14-3

Basic information

• Product Name: N-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]-2-(trideuteriomethylamino)propanamide
• Synonyms: N-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]-2-(trideuteriomethylamino)propanamide
• CAS NO: 1452572-14-3
• Molecular Weight: 377.418
• Mol File: 1452572-14-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]-2-(trideuteriomethylamino)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]-2-(trideuteriomethylamino)propanamide(1452572-14-3)
• EPA Substance Registry System: N-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]-2-(trideuteriomethylamino)propanamide(1452572-14-3)

Safety Data

• Hazardous Substances Data: 1452572-14-3(Hazardous Substances Data)

Upstream product

• 1452573-67-9 tert-butyl N-[1-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-yl]amino]-1-oxopropan-2-yl]-N-(trideuteriomethyl)carbamate 
• 536-74-3 phenylacetylene 
• 1452572-96-1 5-bromo-6-(2-phenylethynyl)pyridin-2-amine 
• 1452573-66-8 5-(3,5-dimethyl-1,2-oxazol-4-yl)-6-(2-phenylethynyl)pyridin-2-amine 
• 89284-11-7 5,6-dibromopyridin-2-ylamine 

Relevant articles and documents

6 - ALKYNYL PYRIDINES AS SMAC MIMETICS

This invention relates to 6-alkynyl-pyridines of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R5 have the meanings given in the claims and in the specification.