14526-01-3

Basic information

• Product Name: 1H-Isoindol-3-amine, N-2-pyridinyl-1-(2-pyridinylimino)-
• CAS NO: 14526-01-3
• Molecular Formula: C18H13N5
• Molecular Weight: 299.335
• Mol File: 14526-01-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Isoindol-3-amine, N-2-pyridinyl-1-(2-pyridinylimino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindol-3-amine, N-2-pyridinyl-1-(2-pyridinylimino)-(14526-01-3)
• EPA Substance Registry System: 1H-Isoindol-3-amine, N-2-pyridinyl-1-(2-pyridinylimino)-(14526-01-3)

Safety Data

• Hazardous Substances Data: 14526-01-3(Hazardous Substances Data)

Usage

Structure

Heterocyclic amine with two pyridine rings and an isoindole ring

Potential applications

Medicinal chemistry and pharmaceutical research, diverse biological activities

Potential therapeutic uses

Anti-cancer agent, other therapeutic uses

Interest to researchers

Drug discovery and development, range of pharmacological properties, treatment of various diseases.

Upstream product

• 504-29-0 2-aminopyridine 
• 119072-55-8 tert-butylisonitrile 
• 7468-67-9 o-formylbenzonitrile 
• 91-15-6 phthalonitrile 

Downstream Products

• 300662-53-7 Cu(II)(1,3-bis(2-pyridylimino)isoindolinate)(O-benzoylsalicylic acid) 
• 300662-52-6 Cu(I)(1,3-bis(2-pyridylimino)isoindoline)(O-benzoylsalicylic acid) 
• 300662-50-4 (Cu(I)(flavonolate)(1,3-bis(2-pyridylimino)isoindoline)) 
• 300662-51-5 (Cu(II)(flavonolate)(1,3-bis(2-pyridylimino)isoindolinate)) 
• 1386999-61-6 (1,3-bis(2-pyridylimino)isoindolato)phenylplatinum(II) 
• 1386999-62-7 (1,3-bis(2-pyridylimino)isoindolato)(p-dimethylaminophenyl)platinum(II) 
• 1211509-97-5 (1,3-bis(2-pyridylimino)isoindoline(-1H))(4-fluorophenylethynyl)platinum(II) 
• 1211510-03-0 (1,3-bis(2-pyridylimino)isoindoline(-1H))(4-(trifluoromethyl)phenylethynyl)platinum(II) 
• 1211509-96-4 (1,3-bis(2-pyridylimino)isoindoline(-1H))(phenylethynyl)platinum(II) 

Relevant articles and documents

Metal free direct formation of various substituted pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5-amines and their further functionalization

Original substituted pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5-amines have been prepared following a Groebke-Blackburn-Bienaymé MCR combined with an N-deprotection and a spontaneous final cyclization step in moderate to good yields. The flexibility of the described method enables the introduction of diverse groups in the 6 and 7 positions on the resulting scaffold using commercially available starting materials. Furthermore, a Buchwald-Hartwig cross coupling with a wide range of aryl and hetaryl halides has been successfully reported using our heterocyclic primary amine derivatives.