1452798-34-3

Upstream product

• 1452798-28-5 (2S,3R)-2-methyloxycarbonylamino-3-trimethylsilylhydroxy-4-iodobutyric acid methyl ester 
• 117136-12-6 7-iodo-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-4,9-dihydro-3H-imidazo<1,2-a>purin-9-one 
• 1452798-23-0 (2S)-2-carboxymethylamino-4-bromo-butyric acid methyl ester 
• 119484-07-0 (2S)-2-methyloxycarbonylaminovinylglycine-O-methyl ester 
• 1452798-25-2 (2S,3R)-2-methyloxycarbonylamino-3,4-epoxybutyric acid methyl ester 
• 177325-78-9 (2S)-2-amino-4-bromo-butyric acid methyl ester hydrobromide 
• 1452798-24-1 (2S)-2-methyloxycarbonylamino-4-phenylselenylbutyric acid methyl ester 
• 1452798-27-4 (2S,3R)-2-methyloxycarbonylamino-3-hydroxy-4-iodobutyric acid methyl ester 
• 88094-82-0 6-methyl-3-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-4,9-dihydro-3H-imidazo[1,2-α]-purin-9-one 
• 6979-94-8 2',3',5'-tri-O-acetyl-guanosine 
• 1452798-29-6 2',3',5'-tri-O-acetyl-1-propargylguanosine 
• 68768-34-3 3,4-Dihydro-4,6-dimethyl-3-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-imidazo<1,2-a>purin-9-one 

Relevant academic research and scientific papers

Total synthesis of the hypermodified RNA bases wybutosine and hydroxywybutosine and their quantification together with other modified RNA bases in plant materials

We report an efficient synthesis of the hypermodified natural tRNA modifications wybutosine (yW) and hydroxywybutosine (OHyW). We also describe the preparation of isotopically labeled analogues for precise quantification of yW and OHyW in different tissue