1452823-84-5

Upstream product

• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 
• 30095-98-8 methyl (2-nitrophenyl)acetate 
• 1316859-98-9 potassium 2-(2-nitrophenyl)acetate 
• 86544-72-1 2-((trifluoromethylsulfonyl)oxy)-1,7,7-trimethylbicyclo<2.2.1>hept-2-ene 

Relevant academic research and scientific papers

Palladium-catalyzed decarboxylative vinylation of potassium nitrophenyl acetate: Application to the total synthesis of (±)-goniomitine

Merge and divert: The natural product (±)-goniomitine was synthesized by a method featuring two key steps: 1) fragment coupling to a functionalized cyclopentene by a novel palladium-catalyzed decarboxylative vinylation reaction and 2) an unprecedented one-pot integrated oxidation/reduction/cyclization (IORC) process to convert the substituted cyclopentene into the tetracyclic skeleton of goniomitine with high chemo-, regio-, and diastereoselectivity.