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SnAP-TM Reagent, developed by the Bode group, is an air and moisture stable compound that can be synthesized from simple reactions using inexpensive raw materials. It is known for its ability to provide a one-step route, in conjunction with various aldehyde substrates, to produce saturated N-heterocycles. The synthesis process requires mild reaction conditions and is compatible with aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups.
Usage:
Used in Chemical Synthesis:
SnAP-TM Reagent is used as a synthetic tool for the creation of saturated N-heterocycles. It is favored for its one-step process, mild reaction conditions, and compatibility with a wide range of aldehyde substrates.
Used in Pharmaceutical Research:
SnAP-TM Reagent is used as a research tool for the development of new pharmaceutical compounds. Its ability to synthesize N-heterocycles, which are common structural elements in many bioactive molecules, makes it a valuable asset in drug discovery and design.
Used in the Bode Research Group:
SnAP-TM Reagent is used as a key component in the research conducted by the Bode Research Group, where it aids in the advancement of chemical synthesis methods and the exploration of novel applications in various scientific fields.

1452829-00-3

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1452829-00-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1452829-00-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,2,8,2 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1452829-00:
(9*1)+(8*4)+(7*5)+(6*2)+(5*8)+(4*2)+(3*9)+(2*0)+(1*0)=163
163 % 10 = 3
So 1452829-00-3 is a valid CAS Registry Number.

1452829-00-3 Well-known Company Product Price

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  • Aldrich

  • (798886)  SnAP TM Reagent  

  • 1452829-00-3

  • 798886-1G

  • 1,516.32CNY

  • Detail

1452829-00-3Relevant academic research and scientific papers

SnAP reagents for the transformation of aldehydes into substituted thiomorpholines - An alternative to cross-coupling with saturated heterocycles

Vo, Cam-Van T.,Mikutis, Gediminas,Bode, Jeffrey W.

supporting information, p. 1705 - 1708 (2013/04/10)

It's a SnAP! The transformation of aldehydes into N-unsubstituted 3-thiomorpholines provides a convenient alternative to metal-catalyzed cross-coupling reactions, which are generally unsuited to the functionalization of saturated N-heterocycles. A copper-mediated radical cyclization is the key to the mild conditions, high functional group tolerance, and broad substrate scope offered by these reagents. Copyright

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