1452839-86-9

Basic information

• Product Name: (S)-2-(3-(1-(quinolin-6-yl)ethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)benzonitrile
• CAS NO: 1452839-86-9
• Molecular Weight: 376.42
• Mol File: 1452839-86-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(3-(1-(quinolin-6-yl)ethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(3-(1-(quinolin-6-yl)ethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)benzonitrile(1452839-86-9)
• EPA Substance Registry System: (S)-2-(3-(1-(quinolin-6-yl)ethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)benzonitrile(1452839-86-9)

Safety Data

• Hazardous Substances Data: 1452839-86-9(Hazardous Substances Data)

Upstream product

• 959585-29-6 methyl 2-(quinolin-6-yl)propanoate 
• 5622-36-6 methyl 2-(quinolin-6-yl)acetate 
• 959585-31-0 6-[1-(6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-ethyl]-quinoline 
• 1151802-25-3 6-[1-(6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-ethyl]-quinoline 
• 959585-30-9 2-(quinolin-6-yl)propanoic Acid 
• 5622-34-4 6-quinoline acetic acid 
• 1197-55-3 4-aminophenylacetic acid 
• 138642-62-3 2-Cyanophenylboronic acid 

Relevant articles and documents

Lessons from (S)-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3- b ]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an inhibitor of receptor tyrosine kinase c-met with high protein kinase selectivity but broad phosphodiesterase family inhibition lea

The hepatocyte growth factor (HGF)/c-Met signaling axis is deregulated in many cancers and plays important roles in tumor invasive growth and metastasis. An exclusively selective c-Met inhibitor (S)-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)- [1,2,4]triazolo[4,3-