145295-40-5Relevant academic research and scientific papers
Synthesis of the sialic acid (-)-KDN and certain epimers from (-)-3-dehydroshikimic acid or (-)-quinic acid
Banwell, Martin G.,Hungerford, Natasha L.,Jolliffe, Katrina A.
, p. 2737 - 2740 (2007/10/03)
(-)-3-Dehydroshikimic acid (3-DHS, 4), a C7-building block now available in large quantity from corn syrup, has been converted into the sialic acid (-)-KDN (3) as well as its C-7- and C-8-epimers. (-)-Quinic acid can be used for the same purpos
Unusual stereoselectivity in sialic acid aldolase-catalyzed aldol condensations: Synthesis of both enantiomers of high-carbon monosaccharides
Lin, Chun-Hung,Sugai, Takeshi,Halcomb, Randall L.,Ichikawa, Yoshitaka,Wong, Chi-Huey
, p. 10138 - 10145 (2007/10/02)
An inversion of stereoselectivity in aldol condensations catalyzed by sialic acid aldolase (from Escherichia coli, Shinko American Inc.) was observed when L-mannose, 6-deoxy-L-mannose, L-talose, 2-deoxy-L-glucose, 2-deoxy-L-rhamnose, N-acetyl-L-mannosamin
