1453-50-5

Basic information

• Product Name: 4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID
• Synonyms: P-XYLYLBUTANOIC ACID;4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID;N-cyclopropylcyclopropanecarboxamide
• CAS NO: 1453-50-5
• Molecular Formula: C₇H₁₁NO
• Molecular Weight: 192.25
• Product Categories: Miscellaneous
• Mol File: 1453-50-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 299.8°Cat760mmHg
• Flash Point: 169.4°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 0.00117mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID(1453-50-5)
• EPA Substance Registry System: 4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID(1453-50-5)

Safety Data

• Hazardous Substances Data: 1453-50-5(Hazardous Substances Data)

Usage

General Description

4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID, also known as DMBA, is a chemical compound with the molecular formula C12H16O2. It is a derivative of butyric acid and contains a 2,5-dimethylphenyl group. DMBA is commonly used as a precursor in the synthesis of various pharmaceuticals and organic compounds. It is also used as a chiral auxiliary in asymmetric synthesis reactions. Additionally, DMBA has been studied for its potential role in the treatment of various medical conditions, including neurological disorders and cancer. 4-(2,5-DIMETHYLPHENYL)BUTYRIC ACID is considered to have low toxicity and is not known to pose significant health risks when handled and used properly.

InChI:InChI=1/C7H11NO/c9-7(5-1-2-5)8-6-3-4-6/h5-6H,1-4H2,(H,8,9)

Upstream product

• 2868-37-3 methyl cyclopropylcarboxylate 
• 765-30-0 Cyclopropylamine 
• 1759-53-1 cyclopropanecarboxylic acid 
• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 1453-52-7 dicyclopropylmethanone oxime 

Downstream Products

• 633317-53-0 (3-[1-(4-chlorophenyl)-trans-3-fluorocyclobutyl]4,5-dicyclopropy1-4H-1,2,4-triazole) 

Relevant articles and documents

Synthesis of N-alkylimidazolium salts and their utility as solvents in the Beckmann rearrangement

Six different room temperature ionic liquids (RTILs) based on N-methyl or N-isopropyl imidazolium cations with counteranions, such as BF4-, PF6-, and OTf-, have been synthesized by exchanging the counteranions of the corresponding N-methyl or N-isopropylimidazolium bromides using appropriate salts such as NH4BF4, KPF6, and AgOTf. Catalytic amounts of these ionic liquids (ILs) have been used as the reaction medium for the Beckmann rearrangement of oximes to amides in the presence of PCl5. A moderate to good conversion of oximes to amides in all the six ILs was observed.

TRIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA HYDROXYSTEROID DEHYDROGENASE-1

Triazole derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM.