1453069-08-3

Upstream product

• 1453069-66-3 (1S,8aS)-tert-butyl 7,7-diallyl-6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate 
• 1453069-65-2 (1S,8aS)-tert-butyl 6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate 
• 1453069-64-1 (1S,8aS)-1-o-tolylhexahydropyrrolo[1,2-a]pyrazin-6(7H)-one 
• 1453069-33-4 benzyl N-(2-{2-[(2-methylphenyl)carbonyl]-5-oxopyrrolidin-1-yl}ethyl)carbamate 
• 1453069-32-3 benzyl N-{2-[5-(2-methylphenyl)pent-4-ynamido]ethyl}carbamate 
• 1228573-50-9 N-[2-(benzyloxycarbonylamino)ethyl]pent-4-ynamide 
• 1453070-32-0 (S)-N,2-dimethyl-N-((R)-1-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenyl)allyl)propane-2-sulfinamide 
• 1453070-31-9 (S)-N-((R)-1-(3-bromo-5-(trifluoromethyl)phenyl)allyl)-N,2-dimethylpropane-2-sulfinamide 
• 1453070-30-8 (S)-N-((R)-1-(3-bromo-5-(trifluoromethyl)phenyl)allyl)-2-methylpropane-2-sulfinamide 
• 1453070-15-9 (1S,8aS)-7,7-diallyl-N-((R)-1-(3-methoxy-5-(trifluoromethyl)phenyl)allyl)-N-methyl-6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide 
• 1453070-13-7 (S)-N-((R)-1-(3-methoxy-5-(trifluoromethyl)phenyl)allyl)-N,2-dimethylpropane-2-sulfinamide 
• 1453070-12-6 (S)-N-((R)-1-(3-hydroxy-5-(trifluoromethyl)phenyl)allyl)-N,2-dimethylpropane-2-sulfinamide 
• 1453069-80-1 (S)-N-(3-bromo-5-(trifluoromethyl)benzylidene)-2-methylpropane-2-sulfinamide 
• 477535-41-4 3-bromo-5-(trifluoromethyl)benzaldehyde 

Relevant academic research and scientific papers

NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS

The present invention relates to a compound according to formula (A) wherein n is 1 or 2; R1 and R2 are independently hydrogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, CD3 or halogen; R3 is hydrogen, C(=O)OR7 or C1-4 alkyl optionally substituted with hyd