145307-55-7

Usage

Uses

Used in Chemical Synthesis:
6-(tert-Butyl-diMethyl-sil... is utilized as a building block for synthesizing other chemicals and materials, such as silicone polymers, due to its versatile chemical structure and reactivity.
Used in Organic Synthesis:
In the realm of organic synthesis, 6-(tert-Butyl-diMethyl-sil... functions as a reagent, contributing to the formation of a range of organic compounds through its ability to participate in various chemical reactions.
Used as a Protecting Group in Organic Chemistry:
6-(tert-Butyl-diMethyl-sil... is employed as a protecting group for alcohols, safeguarding the hydroxyl group from unwanted reactions during complex organic synthesis processes.
Used in Adhesives, Sealants, and Coatings Production:
6-(tert-Butyl-diMethyl-sil... finds application in the production of adhesives, sealants, and coatings, where its chemical properties contribute to the performance characteristics of these materials, such as adhesion, flexibility, and durability.
Safety Considerations:
It is crucial to handle 6-(tert-Butyl-diMethyl-sil... with care, as it can pose health risks. Ingestion or inhalation may be harmful, and it has the potential to cause skin and eye irritation. Proper safety measures should be taken during its use to minimize exposure and ensure the well-being of individuals working with 6-(tert-Butyl-diMethyl-si....

Upstream product

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Downstream Products

• 19186-33-5 aristeromycin 
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Relevant academic research and scientific papers

Highly asymmetric enzymatic hydrolysis and transesterification of meso-bis(acetoxymethyl)- and bis(hydroxymethyl)cyclopentane derivatives: An insight into the active site model of Rhizopus delemar lipase

Rhizopus delemar lipase (RDL)-catalysed hydrolysis of meso-1,3-bis(acetoxymethyl)cyclopentane derivatives (7, 12) and Pseudomonas fluorescens lipase (PFL)-catalysed hydrolysis of 7 afforded the chiral monoacetates (15, 16) of > 99% ee. In explanation of these high enantioselectivities of RDL, the simple box-type active site model of enzyme was tentatively proposed. On the other hand, PFL-catalysed transesterification of meso-bis-(hydroxymethyl)cyclopentane (6) afforded (+)-16 of > 99% ee. The obtained (+) and (-)-16 were converted into the natural carbocyclic nucleoside(-)-aristeromycin (25), respectively.

Investigations of Aristeromycin Biosynthesis: Evidence for the Intermediacy of a 2α,3α-Dihydroxy-4β-(hydroxymethyl)cyclopentane-1β-amine

Administration of doubly-labelled forms of D-glucose to the fermentation broth of Streptomyces citricolor followed by isotopic trapping has provided evidence for the intermediacy of a 2α,3α-dihydroxy-4β-(hydroxymethyl)cyclopentane-1β-amine 7 or 8 in the biosynthesis of the nucleoside antibiotic aristeromycin 1.

Tumor immunity compound and application thereof

Disclosed are a tumor immunity compound and an application thereof. The invention discloses a compound as shown in the formula (I), optical isomers thereof, and pharmaceutically acceptable salts thereof, and an application of the compound as an STING agonist.

A General Biomimetic Hetero-Diels-Alder Approach to the Core Skeletons of Xenovulene A and the Sterhirsutins A and B

A biomimetic, regio- and stereoselective approach to the 5,6,11-tricyclic core skeleton of xenovulene A, as well as sterhirsutins A and B, is described. The key steps are a biomimetic inverse-electron-demand hetero-Diels-Alder cycloaddition of α-humulene and a ribose-derived vinyl ketone, followed by acid-catalyzed rearrangement of the 1,3-dioxolane that neighbors the resultant cyclic enol ether.