1453101-55-7Relevant academic research and scientific papers
Mild rhodium(III)-catalyzed cyclization of amides with α,β- unsaturated aldehydes and ketones to azepinones: Application to the synthesis of the homoprotoberberine framework
Shi, Zhuangzhi,Grohmann, Christoph,Glorius, Frank
supporting information, p. 5393 - 5397 (2013/06/05)
Seven! The title reaction can be described as an intermolecular annulation involving tandem C-H activation, cyclization to give the seven-membered ring, and condensation steps. Biologically interesting azepinone derivatives can be prepared in this way. Th
