1453124-68-9

Upstream product

• 23165-29-9 3,5-bistrifluoromethylphenylisothiocyanate 
• 48107-55-7 2,5-diamino-1,4:3,6-dianhydro-2,5-dideoxy-L-iditol,DAI 
• 54522-28-0 (3R,3aS,6R,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-methylbenzenesulfonate) 
• 641-74-7 1,4:3,6-dianhydro-D-mannitol 

Relevant academic research and scientific papers

Asymmetric Michael addition of acetone to β-nitrostyrenes catalyzed by novel organocatalysts derived from D-isomannide or Lisoidide

Novel bifunctional organocatalysts were prepared from D-isomannide or L-isoidide in three steps. These catalysts were then evaluated in the asymmetric Michael addition of acetone to trans-.-nitrostyrenes. Although moderate enantioselectivities were observed, this study has highlighted that a simple chiral primary diamine can catalyze this reaction. Furthermore, the reaction was also performed with an isomannide-derived diimine which was transformed in situ into the active catalyst under acidic conditions leading to the best enantioselectivity. ARKAT-USA, Inc.

Dianhydrohexitols: New tools for organocatalysis. Application in enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes

A series of hydrogen bonding organocatalysts was synthesized from dianhydrohexitol and was used for the first time in organocatalysis for Friedel-Crafts alkylation of indoles with nitroalkenes. Moderate yields and enantioselectivities were achieved. ARKAT