145317-23-3Relevant academic research and scientific papers
Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction
Bit,Davis,Elliott,Harris,Hill,Keech,Kumar,Lawton,Maw,Nixon,Vesey,Wadsworth,Wilkinson
, p. 21 - 29 (1993)
The protein kinase inhibitor staurosporine has been used to design a series of selective bisindolylmaleimide inhibitors of protein kinase C (PKC). Guided by molecular graphics, conformational restriction of the cationic side chain has led to ATP competiti
