1453172-63-8Relevant academic research and scientific papers
Synthesis of dibenzoxepine lactams via a Cu-catalyzed one-pot etherification/aldol condensation cascade reaction: Application toward the total synthesis of aristoyagonine
Lim, Hye Sun,Choi, Young Lok,Heo, Jung-Nyoung
supporting information, p. 4718 - 4721 (2013/10/08)
A general synthesis of dibenzoxepine lactams has been developed using a one-pot Cu-catalyzed etherification/aldol condensation cascade reaction. The reaction of 4-hydroxyisoindolin-1-one with a wide range of 2-bromobenzaldehydes in the presence of a copper catalyst provided various aristoyagonine derivatives in good yields.
