1453217-79-2Relevant articles and documents
A constrained tricyclic nucleic acid analogue of α-l-LNA: Investigating the effects of dual conformational restriction on duplex thermal stability
Hanessian, Stephen,Wagger, Jernej,Merner, Bradley L.,Giacometti, Robert D.,stergaard, Michael E.,Swayze, Eric E.,Seth, Punit P.
, p. 9064 - 9075 (2013)
A constrained tricyclic analogue of α-l-LNA (2), which contains dual modes of conformational restriction about the ribose sugar moiety, has been synthesized and characterized by X-ray crystallography. Thermal denaturation experiments of oligonucleotide se