1453267-75-8

Upstream product

• 573768-09-9 4-amino-2-chloro-3-methyl-benzonitrile 
• 864271-07-8 2-chloro-4-isothiocyanato-3-methylbenzonitrile 
• 1453267-33-8 2-(methoxymethoxy)-1-(methylamino)cyclopentanecarbonitrile 
• 1453267-32-7 2-(methoxymethoxy)cyclopentanol 
• 142-29-0 cyclopentene 
• 4065-92-3 cyclopentane-1,2-diol 

Downstream Products

• 1453266-48-2 2-chloro-4-((5R,6S)-6-hydroxy-1-methyl-2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-3-methylbenzonitrile 
• 1453266-49-3 2-chloro-4-((5S,6R)-6-hydroxy-1-methyl-2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-3-methylbenzonitrile 
• 1453266-50-6 2-chloro-4-((5R,6R)-6-hydroxy-1-methyl-2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-3-methylbenzonitrile 
• 1453266-51-7 2-chloro-4-((5S,6S)-6-hydroxy-1-methyl-2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-3-methylbenzonitrile 

Relevant academic research and scientific papers

SPIROHYDANTOIN COMPOUNDS AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The present invention relates to a compound of formula (1-1 ) in free form or in pharmaceutically acceptable salt form in which the substituents are as defined in the specification; to its preparation, to its use as a medicament and to medicaments comprising it. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.