1453470-18-2Relevant academic research and scientific papers
Convergent access to bis-spiroacetals through a sila-Stetter-ketalization cascade
Labarre-Laine, Jessica,Beniazza, Redouane,Desvergnes, Valerie,Landais, Yannick
supporting information, p. 4706 - 4709 (2013/10/08)
An NHC-catalyzed sila-Stetter reaction between aliphatic acylsilanes and vinylketones bearing silyl ether substituents affords functionalized 1,4-diketones, which upon treatment under acidic conditions leads to the corresponding bis-spiroacetals. The two-step sequence may also be carried out in a one-pot operation leading to high yields of the desired bis-spiroacetals.
