1453490-86-2Relevant academic research and scientific papers
N -Sulfonyl α-imino ester-derived chiral oxaziridines: Catalytic asymmetric synthesis and application as a modular chiral organic oxidant
Tanaka, Naoya,Tsutsumi, Ryosuke,Uraguchi, Daisuke,Ooi, Takashi
, p. 6999 - 7002 (2017)
A novel class of chiral N-sulfonyl oxaziridines is introduced for use as structurally modifiable chiral oxidants. These oxaziridines are readily prepared from N-sulfonyl α-imino esters in a highly enantioenriched form by oxidation with hydrogen peroxide using l-isoleucine-derived triaminoiminophosphorane as a catalyst. The distinct advantage of their structural modularity is demonstrated through the identification of an optimal oxaziridine that exhibits high reactivity and enantiospecificity in the asymmetric oxidation of a silyl enol ether and N-sulfonyl allylic and homoallylic amines.
P-chirogenic organocatalysts: Application to the aza-Morita-Baylis-Hillman (aza-MBH) reaction of ketimines
Takizawa, Shinobu,Remond, Emmanuelle,Arteaga, Fernando Arteaga,Yoshida, Yasushi,Sridharan, Vellaisamy,Bayardon, Jerome,Juge, Sylvain,Sasai, Hiroaki
supporting information, p. 8392 - 8394 (2013/09/23)
The P-chirogenic organocatalysts were found to promote the enantioselective aza-Morita-Baylis-Hillman reaction of ketimines derived from acyclic α-keto esters. In the P-chirogenic organocatalyzed aza-MBH reactions, α,α-disubstituted α-amino acid derivativ
