145355-25-5

Upstream product

• 1360114-41-5 C₁₃H₁₀BrN₃O₂ 
• 119216-06-7 (3,6-dichloro-pyridazin-4-yl)-phenyl-methanone 
• 145355-23-3 (3-amino-6-chloro-4-pyridazinyl) phenyl ketone 

Downstream Products

• 145355-36-8 7-(4-ethylpiperazinyl)-5-phenylpyrido<2,3-c>pyridazine 
• 145355-35-7 7-dimethylamino-5-phenylpyrido<2,3-c>pyridazine 

Relevant academic research and scientific papers

Novel access to 1,4-benzodiazepin-2-ones via the Buchwald reaction and application to the synthesis of novel heterocyclics

A new two step strategy for the preparation of 1,4-benzodiazepin-2-ones has been developed starting from the 2-halogenobenzophenone under Buchwald conditions (Pd(OAc)2, XantPhos, Cs2CO3, dioxane 100 °C). This strategy has

(3-Amino-4-pyridazinyl)phenyl ketones as novel 2-aminobenzophenone isosters: Synthesis and conversion into pyrido[2,3-c]pyridazines. 64th Communication: Syntheses and reactions of pyridazines

The preparation of novel diaza analogs of 2-aminobenzophenone (compounds 4, 6) is described. The utility of these bifunctional pyridazine derivatives for the construction of potentially bio-active pyrido[2,3-c]pyridazines is demonstrated.

RECENT ADVANCES IN PYRIDAZINE CHEMISTRY

Efficient syntheses of a variety of so far not accessible, monosubstituted or vicinally disubstituted 1,2-diazine derivatives are presented.The versatility of these compounds for syntheses of various polyaza bicyclic and tricyclic systems is demonstrated.