145383-00-2

Basic information

• Product Name: N-((4-chlorobenzyl)carbamothioyl)benzamide
• Synonyms: N-((4-chlorobenzyl)carbamothioyl)benzamide
• CAS NO: 145383-00-2
• Molecular Weight: 304.8
• Mol File: 145383-00-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-((4-chlorobenzyl)carbamothioyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((4-chlorobenzyl)carbamothioyl)benzamide(145383-00-2)
• EPA Substance Registry System: N-((4-chlorobenzyl)carbamothioyl)benzamide(145383-00-2)

Safety Data

• Hazardous Substances Data: 145383-00-2(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 106-47-8 4-chloro-aniline 
• 532-55-8 Benzoyl isothiocyanate 

Downstream Products

• 1014977-69-5 C₄₀H₃₅ClN₄OS 
• 24827-37-0 N-(4-chlorobenzyl)thiourea 
• 145231-35-2 Clobenpropit dihydrobromide 

Relevant articles and documents

Structural Effect of Pincer Pd(II)–ONO Complexes Modified with Acylthiourea on Sizes of the In Situ Generated Pd Nanoparticles During Heck Coupling Reaction

Abstract: The Pd nanoparticles generated in situ from Pd–pincer complexes catalyzed Heck coupling reaction. For this purpose, new Pd(II)–ONO pincer complexes (1–4) containing acylthiourea ancillary ligand were obtained by treating [Pd(ONO)(CH3CN)] with the respective N-substituted carbamothioyl benzamide ligand (L1–L4). Formation of these complexes was confirmed by UV–Visible, FT-IR, NMR and mass spectroscopic techniques. The sizes of in situ formed Pd nanoparticles were greatly affected by the substituent in ancillary ligand, which in turn influenced their catalytic activity towards Heck coupling reaction. The in situ formed Pd nanoparticles during Heck reaction were removed from the reaction medium and analyzed using HR-TEM to estimate the sizes of the Pd nanoparticles. Complex [Pd(ONO)((N-benzylcarbamothioyl)benzamide)] (1) which does not possess any substituent on the benzyl moiety of acylthiourea produced the smallest Pd nanoparticles with the average particle size of 3.7?nm. Hence, complex 1 showed the utmost catalytic activity. With complex 1, 51–99% of conversion was observed during Heck coupling reaction of styrene with various aryl halides. XPS results confirmed that the recovered black particles were Pd(0). A reasonable recyclability results were achieved by these in situ generated Pd nanoparticles. Graphic Abstract: [Figure not available: see fulltext.]

NOVEL THIOUREA OR UREA DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING AIDS, CONTAINING SAME AS ACTIVE INGREDIENT

Disclosed are novel thiourea or urea derivatives inhibitory of HIV activity. Also provided are a method for preparing the thiourea or urea derivatives, and a pharmaceutical composition for the prophylaxis or therapy of AIDS comprising the derivatives. Hav