1453856-71-7Relevant academic research and scientific papers
Stereoselective synthesis of 2,3-dihydropyrroles from terminal alkynes, azides, and α,β-unsaturated aldehydes via N-sulfonyl-1,2,3-triazoles
Miura, Tomoya,Tanaka, Takamasa,Hiraga, Kentaro,Stewart, Scott G.,Murakami, Masahiro
, p. 13652 - 13655 (2013)
A stereoselective method for synthesis of trans-2,3-disubstituted 2,3-dihydropyrroles is reported. N-Sulfonyl-1,2,3-triazoles prepared from terminal alkynes generate α-imino rhodium carbene complexes, which when combined with α,β-unsaturated aldehydes produce trans-2,3- disubstituted dihydropyrroles. The method can be successfully applied to a one-pot process starting from terminal alkynes.
