145439-15-2 Usage
Uses
Used in Pharmaceutical Research and Development:
1-(4-Chloro-1H-indazol-1-yl)ethanone is used as a key intermediate in the synthesis of potential drug molecules, particularly due to its unique chemical properties and the presence of a chloro-substituted indazole ring. Its versatility in chemical reactions makes it a valuable component in the development of new pharmaceuticals.
Used in Organic Synthesis:
In the chemical industry, 1-(4-Chloro-1H-indazol-1-yl)ethanone serves as a valuable intermediate for the synthesis of various organic compounds. The presence of the ketone functional group allows for a range of chemical reactions, facilitating the creation of diverse organic molecules for different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 145439-15-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,4,3 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145439-15:
(8*1)+(7*4)+(6*5)+(5*4)+(4*3)+(3*9)+(2*1)+(1*5)=132
132 % 10 = 2
So 145439-15-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2O/c1-6(13)12-9-4-2-3-8(10)7(9)5-11-12/h2-5H,1H3
145439-15-2Relevant academic research and scientific papers
On the behaviour of 4- or 7-chloro-2-nitroindazole against cyclic amines. Part 35: Azoles
Majewska,Wrzeciono
, p. 688 - 691 (2007/10/02)
The nitration of 4- or 7-chloroindazole (1, 9) to 4- or 7-chloro-2-nitroindazole (2, 11) is described. 4- or 7-chloro-3-nitroindazole (3, 12) and 4-chloro-1-nitroindazole (4) have been isolated as by-products. On treating with morpholine, pyrrolidine, piperidine and N-methylpiperazine 2 and 11 are transformed to the corresponding 3-amino-4- or 7-chloroindazoles 5-8,13-16 and 4- or 7-chloro-3-nitroindazole (3, 12). The isomerization of 2 to 3 takes also place under the influence of temperature.
Aromatic Diazonium Salts, X. - A One-Pot Procedure for the Jacobson Synthesis of Indazole
Ruechardt, Christoph,Hassmann, Volker
, p. 908 - 927 (2007/10/02)
Procedures are described for a one-pot synthesis of 1H-indazole and substituted indazoles 3 in good yield (Table 1) from o-toluidines 2, alkyl nitrite or nitrous oxides, potassium acetate, and acetic anhydride in benzene.The spectroscopic properties of substituted indazoles (Tables 2-4) are discussed. - 4-Phenylcinnoline (18) is prepared by the same procedure from o-(α-methylenebenzyl)aniline.
