145449-37-2

Upstream product

• 96-32-2 bromoacetic acid methyl ester 
• 15946-36-8 2-chlorobenzenesulfinic acid sodium salt 
• 67-56-1 methanol 
• 82224-89-3 (2-Chloro-benzenesulfonyl)-acetic acid 

Downstream Products

• 17482-05-2 o-chlorophenyl methyl sulfone 
• 17733-22-1 2-chlorothioanisole 
• 97189-47-4 5-Methylthio-2-thioxo-1,3-dithiol-4-carbonsaeuremethylester 

Relevant academic research and scientific papers

Reactions of Arylsulphonyl, Arylthio and Acyl Acetates with S-Containing Heterocumulenes

The reaction of arylsulphonyl- or (phenylthio)-acetates 1 with carbon disulphide in a basic medium led to the corresponding ketene dithioacetals 2 in good yields.The o-chloro derivative 1d gave with carbon disulphide various products under different reaction conditions.However, the reaction of 1 with phenyl isothiocyanate primarily resulted in N-substituted pyrimidone derivatives 9, except for 1e which mainly gave S,N-analogues of dithioacetals 10e and 10f. β-Ketoesters 1g, h also reacted with phenyl isothiocyanate to afford 5-acyl-2-thioxo-4-pyrimidones 9g, h.The dependency of the polarisation of the double bond in ketene dithioacetals and their S,N-analogues on acceptor groups was investigated with the help of 13C NMR spectroscopy.

Applicability of Hammett Equation to Kinetics of Acid-catalysed Esterification of ortho-Substituted Phenoxyacetic, Phenylmercaptoacetic and Phenylsulphonylacetic Acids by Methanol

Correlation analysis of the title rate data shows that the steric effects of ortho-substituents are absent at the reaction centre.