145457-85-8

Upstream product

• 14527-26-5 2-methylisothiourea sulphate 
• 145457-83-6 2-(5-tert-butyldimethylsilyloxy)-pentylthiobromobenzene 
• 145457-84-7 2-[5-(tert-Butyl-dimethyl-silanyloxy)-pentylsulfanyl]-benzaldehyde 
• 17165-45-6 2-(trimethylsilyl)ethyl acetoacetate 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 85514-44-9 <(5-Chloropentyl)oxy>-dimethyl-tert-butylsilane 
• 6320-02-1 o-bromothiophenol 

Downstream Products

• 145457-86-9 6-{2-[5-(tert-Butyl-dimethyl-silanyloxy)-pentylsulfanyl]-phenyl}-4-methyl-2-methylsulfanyl-6H-pyrimidine-1,5-dicarboxylic acid 1-tert-butyl ester 5-(2-trimethylsilanyl-ethyl) ester 
• 145457-87-0 6-[2-(5-Hydroxy-pentylsulfanyl)-phenyl]-4-methyl-2-methylsulfanyl-6H-pyrimidine-1,5-dicarboxylic acid 1-tert-butyl ester 

Relevant academic research and scientific papers

Calcium entry blockers and activators: Conformational and structural determinants of dihydropyrimidine calcium channel modulators

Dihydropyrimidines 4, 6, and 15, uniquely designed to unambiguously establish structural and conformational determinants for DHP receptor occupation and for modulation of calcium channel function, were prepared and examined for calcium channel modulation.

Dihydropyrimidine macrocyclic lactones useful as calcium antagonists and agonists

A compound of the formula STR1 (symbols defined in the specification), its 3,4-dihydropyrimidine tautomer form and pharmaceutically acceptable salts thereof have calcium entry blocking activity. A process of preparation, pharmaceutical composition and met