1454575-12-2Relevant academic research and scientific papers
Synthesis and biological activities of fluorinated 10-hydroxycamptothecin and SN38
Wu, Yuelin,Zhu, Lingjian,Sheng, Chunquan,Yao, Jianzhong,Miao, Zhenyuan,Zhang, Wannian,Wei, Yunyang,Shi, Ruofu
, p. 48 - 51 (2014/01/06)
It is an important strategy for fluorine substitution in drug design because of its small size and high electronegativity. Fluorinated 10-hydroxycamptothecin and SN 38 were prepared and screened for antiproliferative activities. Among them, fluorinated co
