145471-63-2Relevant academic research and scientific papers
Stereocontrolled Annulations of Indolo[2,3-a]quinolizidine-Derived Lactams with a Silylated Nazarov Reagent: Access to Allo and Epiallo Yohimbine-Type Derivatives
Arioli, Federica,Pérez, Maria,Are, Celeste,Estarellas, Carolina,Luque, F. Javier,Bosch, Joan,Amat, Mercedes
, p. 13382 - 13389 (2015/09/15)
The facial selectivity of double Michael addition reactions of the silylated Nazarov reagent 4 to unsaturated indolo[2,3-a]quinolizidine lactams 3 has been studied. Pentacyclic 3-H/15-H trans adducts 5 are generated from Nind-unsubstituted lact
A New ABCDE> Cycloaddition Strategy for the Approach to Yohimbe Alkaloids: Stereoselective Synthesis of (+/-)-3-epi-allo-Yohimbone
Gomez-Pardo, Domingo,d'Angelo, Jean
, p. 6637 - 6640 (2007/10/02)
Diels-Alder cycloaddition between lactam-sulfone 9 and diene 10 led to adducts 11 + 12 (30:1, respectively).Compound 11 has been converted in 4 steps into (+/-)-3-epi-allo-yohimbone 16.Key words: Diels-Alder cycloaddition, Yohimbe alkaloids, (+/-)-3-epi-a
