1454797-89-7

Basic information

• Product Name: ethyl 2,3,3-tris(3,4-dimethoxyphenyl)propionate
• Synonyms: ethyl 2,3,3-tris(3,4-dimethoxyphenyl)propionate
• CAS NO: 1454797-89-7
• Molecular Weight: 510.584
• Mol File: 1454797-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2,3,3-tris(3,4-dimethoxyphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,3,3-tris(3,4-dimethoxyphenyl)propionate(1454797-89-7)
• EPA Substance Registry System: ethyl 2,3,3-tris(3,4-dimethoxyphenyl)propionate(1454797-89-7)

Safety Data

• Hazardous Substances Data: 1454797-89-7(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 2859-78-1 4-Bromoveratrole 
• 18066-68-7 ethyl 3,4-dimethoxyphenylacetate 
• 74084-26-7 3,3',4,4'-tetramethoxybenzhydrole 

Downstream Products

• 1454797-88-6 2,3,3-tris(3,4-dimethoxyphenyl)propan-1-ol 

Relevant articles and documents

Synthesis and antiproliferative activities of quebecol and its analogs

Simple and efficient synthesis of quebecol and a number of its analogs was accomplished in five steps. The synthesized compounds were evaluated for antiproliferative activities against human cervix adenocarcinoma (HeLa), human ovarian carcinoma (SK-OV-3), human colon carcinoma (HT-29), and human breast adenocarcinoma (MCF-7) cancer cell lines. Among all the compounds, 7c, 7d, 7f, and 8f exhibited antiproliferative activities against four tested cell lines with inhibition over 80% at 75 μM after 72 h, whereas, compound 7b and 7g were more selective towards MCF-7 cell line. The IC50 values for compounds 7c, 7d, and 7f were 85.1 μM, 78.7 μM, and 80.6 μM against MCF-7 cell line, respectively, showing slightly higher antiproliferative activtiy than the synthesized and isolated quebecol with an IC50 value of 104.2 μM against MCF-7.