18066-68-7

Basic information

• Product Name: ETHYL 3,4-DIMETHOXYPHENYLACETATE
• Synonyms: 3,4-dimethoxy-benzeneaceticaciethylester;Acetic acid, (3,4-dimethoxyphenyl)-, ethyl ester;Benzeneacetic acid, 3,4-dimethoxy-, ethyl ester;Ethyl dimethoxyphenylacetate;ETHYL 3,4-DIMETHOXYPHENYLACETATE;ETHYL 2-(3,4-DIMETHOXYPHENYL)ACETATE;HOMOVERATRIC ACID ETHYL ESTER;3,4-Dimethoxyphenylacetic acid ethyl ester~Ethyl homoveratrate
• CAS NO: 18066-68-7
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25
• EINECS: 241-974-9
• Product Categories: Catechol Derivatives;Aromatic Esters
• Mol File: 18066-68-7.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 191 °C
• Flash Point: 159-160°C/4mm
• Appearance: /
• Density: 1.084 g/cm³
• Vapor Pressure: 0.00102mmHg at 25°C
• Refractive Index: 1.5180
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2697968
• CAS DataBase Reference: ETHYL 3,4-DIMETHOXYPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3,4-DIMETHOXYPHENYLACETATE(18066-68-7)
• EPA Substance Registry System: ETHYL 3,4-DIMETHOXYPHENYLACETATE(18066-68-7)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• TSCA: Yes
• Hazardous Substances Data: 18066-68-7(Hazardous Substances Data)

Usage

General Description

ETHYL 3,4-DIMETHOXYPHENYLACETATE is a chemical compound with the formula C12H16O4. It is a ester, specifically an ethyl ester, of 3,4-dimethoxyphenylacetic acid. ETHYL 3,4-DIMETHOXYPHENYLACETATE is commonly used as a flavoring agent in the food industry due to its sweet and fruity aroma, and it is also used in the production of perfumes and fragrances. Additionally, it has some potential applications in the pharmaceutical industry, as it has been studied for its potential antioxidant and anti-inflammatory properties. However, its use in pharmaceuticals is limited due to its potential for toxicity at high concentrations, and it should be handled and used with caution.

InChI:InChI=1/C12H16O4/c1-4-16-12(13)8-9-5-6-10(14-2)11(7-9)15-3/h5-7H,4,8H2,1-3H3

Upstream product

• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 64-17-5 ethanol 
• 91-16-7 1,2-dimethoxybenzene 
• 34006-60-5 ethyl 2-chloro-2-ethoxyacetate 
• 40233-98-5 3,4-dimethoxyphenylglyoxylic acid ethyl ester 
• 81316-62-3 ethyl 2-(3,4-dimethoxyphenyl)acetoimidate hydrochloride 
• 7664-93-9 sulfuric acid 
• 10035-10-6 hydrogen bromide 
• 64-19-7 acetic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 35323-09-2 (2-iodo-4,5-dimethoxyphenyl)acetic acid 
• 470662-16-9 ethyl 2-(2-iodo-4,5-dimethoxyphenyl)acetate 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 35453-08-8 1-Methylsulfinyl-1-methylthio-2-(3,4-dimethoxyphenyl)-ethylen 

Downstream Products

• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 10313-64-1 N-(2,3-dimethoxyphenylethyl)-2-(3,4-dimethoxyphenyl)acetamide 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 5663-56-9 2-(3,4-dimethoxyphenyl)acetamide 
• 60075-23-2 3,4-dimethoxyphenylacetic acid hydrazide 
• 90149-75-0 ethyl 2-acetyl-4,5-dimethoxyphenylacetate 
• 40940-49-6 ethyl 2-<2'-<1''-(3,4-dimethoxyphenyl)-2''-oxoethyl>-4',5'-dimethoxyphenyl>acetic acid 
• 56203-23-7 2-(3,4-Dimethoxy-phenyl)-N-[2-(2-hydroxy-2-phenyl-ethylamino)-ethyl]-acetamide 
• 119540-39-5 3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-2-(3,4-dimethoxy-phenyl)-propionic acid ethyl ester 
• 107300-87-8 2-[5-(3,4-Dimethoxy-benzyl)-[1,2,4]oxadiazol-3-yl]-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-acetamide 
• 114855-48-0 triethyl 1,3-bis(3,4-dimethoxyphenyl)propane-1,2,2-tricarboxylate 
• 53979-19-4 diethyl 2-(3,4-dimethoxybenzyl)malonate 
• 107300-98-1 N-[2-(3,4-Diethoxy-phenyl)-ethyl]-2-[5-(3,4-dimethoxy-benzyl)-[1,2,4]oxadiazol-3-yl]-acetamide 
• 91881-19-5 ethyl (2-bromo-4,5-dimethoxyphenyl)acetate 

Relevant articles and documents

NURR1 RECEPTOR MODULATORS

Described herein, inter alia, are Nurr1 receptor modulators and uses thereof. In an aspect is provided a method for treating a disease associated with dysregulation and/or degeneration of dopaminergic neurons in the central nervous system of a subject in need thereof, the method including administering to the subject in need thereof a therapeutically effective amount of a compound described herein.

Rapid Assembly of Saturated Nitrogen Heterocycles in One-Pot: Diazo-Heterocycle “Stitching” by N–H Insertion and Cyclization

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Nature and kinetic analysis of carbon-carbon bond fragmentation reactions of cation radicals derived from SET-oxidation of lignin model compounds

Features of the oxidative cleavage reactions of diastereomers of dimeric lignin model compounds, which are models of the major types of structural units found in the lignin backbone, were examined. Cation radicals of these substances were generated by using SET-sensitized photochemical and Ce(IV) and lignin peroxidase promoted oxidative processes, and the nature and kinetics of their C- bond cleavage reactions were determined. The results show that significant differences exist between the rates of cation radical C1-2 bond cleavage reactions of 1,2-diaryl-(β-1) and 1-aryl-2-aryloxy-(β-O-4) propan-1,3-diol structural units found in lignins. Specifically, under all conditions C1-2 bond cleavage reactions of cation radicals of the β-1 models take place more rapidly than those of the β-O-4 counterparts. The results of DFT calculations on cation radicals of the model compounds show that the C1-2 bond dissociation energies of the β-1 lignin model compounds are significantly lower than those of the β-O-4 models, providing clear evidence for the source of the rate differences.