1454807-85-2

Upstream product

• 84806-48-4 methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate 
• 96-34-4 methyl chloroacetate 
• 62-53-3 aniline 
• 604756-32-3 methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate 
• 98-80-6 phenylboronic acid 

Relevant academic research and scientific papers

[6,6] FUSED BICYCLIC HDAC8 INHIBITORS

The present invention is directed to compounds of Formula I: and pharmaceutically acceptable salts, prodrugs, solvates, hydrates, tautomers, or isomers or thereof, wherein R1, R2, R2', L, X, W, Y1,Y2,

Cascade reaction between methyl 3-dehydroshikimate, arylamines, and 2-chloroalkyl esters under microwave conditions: A practical and biomass-based synthesis of N -aryl-1,4-benzoxazin-3-ones

A biomass-based, metal- and ligand-free assembly of N-aryl-1,4-benzoxazin- 3-ones from methyl 3-dehydroshikimate (3-MHDS), involving aliphatic to aromatic transformation followed by C-O and C-N forming reactions, is presented. A variety of N-aryl-1,4-benzoxazin-3-ones were efficiently synthesized in a one-pot consecutive manner under microwave conditions. Georg Thieme Verlag Stuttgart, New York.