84806-48-4

Basic information

• Product Name: methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate
• Synonyms: methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate
• CAS NO: 84806-48-4
• Molecular Weight: 186.164
• Mol File: 84806-48-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate(84806-48-4)
• EPA Substance Registry System: methyl (4S,5R)-4,5-dihydroxy-3-oxo-1-cyclohexene-1-carboxylate(84806-48-4)

Safety Data

• Hazardous Substances Data: 84806-48-4(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 2922-42-1 (-)-3-dehydroshikimic acid 
• 67-56-1 methanol 
• 10534-44-8 3-dehydroquinic acid 
• 57764-14-4 methyl 3-dehydroquinate 
• 77-95-2 D-(-)-quinic acid 
• 40983-58-2 methyl shikimate 
• 138-59-0 shikimic acid 

Downstream Products

• 40983-58-2 methyl shikimate 
• 171963-38-5 methyl [3S-(3α,4β,5α)]-3,4,5-trihydroxy-1-cyclohexene-1-carboxylate 
• 100885-52-7 (4R)-3-(2,4-dinitro-phenylhydrazono)-4r,5t-dihydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 148694-46-6 (4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 148694-48-8 (4R,5R)-4,5-Dihydroxy-3-methylene-cyclohex-1-enecarboxylic acid methyl ester 
• 148694-50-2 methyl 3-homoshikimate 
• 148694-51-3 (3S,4R,5R)-3-(Dimethoxy-phosphoryloxymethyl)-4,5-dihydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 148694-47-7 (4R,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-methylene-cyclohex-1-enecarboxylic acid methyl ester 
• 1356144-15-4 methyl 3,4-dihydroxy-5-(propylamino)benzoate 
• 1356144-05-2 methyl 3-(2,6-diethylphenylamino)-4-hydroxybenzoate 
• 1356144-01-8 methyl 3-(2,5-dichlorophenylamino)-4-hydroxybenzoate 
• 1356144-23-4 methyl 3-(hexylamino)-4,5-dihydroxybenzoate 
• 1356144-07-4 methyl 3-(2-(diphenylmethylene)hydrazinyl)-4-hydroxybenzoate 
• 1356144-21-2 methyl 3,4-dihydroxy-5-(isobutylamino)benzoate 

Relevant articles and documents

Novel 4-benzamino-benzofuran[2,3-d]pyridine compound and application thereof

The invention discloses a novel 4-benzamino-benzofuran[2,3-d]pyridine compound and application thereof. The 4-benzamino-benzofuran[2,3-d]pyridine compound as shown in a general formula (I) as well asa pharmaceutically acceptable salt, a hydrate, a solvate or a predrug with anti-tumor effect. The experiment proves that the 4-benzamino-benzofuran[2,3-d]pyridine compound has a good inhibition effecton human lung adenocarcinoma cells A549, human large cell lung cancer cells H460 and Gefitinib medicine-resistant human lung adenocarcinoma cell strains H1975 (containing high-expression T790M/L858 double-mutation EGFR) and can be used for preparing anti-tumor medicines. (The formula is as shown in the description).

Sequential C-C, C-O, and C-N bond-forming reaction of methyl (-)-3-dehydroshikimate, malononitrile, and bromoalkanes: Simple synthesis of 2-(alkylamino)-3-cyanobenzofurans from a biomass-derived substrate

An interesting and simple method was developed for the synthesis of 2-(alkylamino)-3-cyanobenzofurans by consecutive C-C, C-O, and C-N coupling reaction of methyl (-)-3-dehydroshikimate with malononitrile and a bromoalkane or dibromoalkane under microwave

Bio-based synthesis of secondary arylamines from (-)-shikimic acid

A specific family of secondary arylamines, including diarylamines and arylalkylamines have been synthesized in good yields starting from the renewable and biomass-based feedstock (-)-shikimic acid (1). The tandem cross-coupling and aromatization reactions