1455093-94-3

Basic information

• Product Name: 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid methyl ester
• Synonyms: 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid methyl ester
• CAS NO: 1455093-94-3
• Molecular Weight: 419.437
• Mol File: 1455093-94-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid methyl ester(1455093-94-3)
• EPA Substance Registry System: 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid methyl ester(1455093-94-3)

Safety Data

• Hazardous Substances Data: 1455093-94-3(Hazardous Substances Data)

Upstream product

• 945740-36-3 1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carboxylic acid butyl ester 
• 25307-82-8 methyl 3-amino-2,2-dimethylpropionate 

Downstream Products

• 1455089-57-2 3-[(1-cyano-4-hydroxy-6-phenoxyisoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid 

Relevant articles and documents

4 -HYDROXY- ISOQUINOLINE COMPOUNDS AS HIF HYDROXYLASE INHIBITORS

The present invention relates to novel compounds of formula (I), and compositions capable of inhibiting PHD1 enzyme activity selectively over other isoforms, for example, PHD2 and/or PHD3 enzymes. The invention also relates to compounds of formula (I) for use in disorders such as muscle degeneration, colitis, IBD, and certain ischemias.