1455396-80-1

Basic information

• Product Name: (E)-dimethyl 2-(3-(p-tolyl)allyl)-2-(trifluoromethyl)malonate
• Synonyms: (E)-dimethyl 2-(3-(p-tolyl)allyl)-2-(trifluoromethyl)malonate
• CAS NO: 1455396-80-1
• Molecular Weight: 330.304
• Mol File: 1455396-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-dimethyl 2-(3-(p-tolyl)allyl)-2-(trifluoromethyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-dimethyl 2-(3-(p-tolyl)allyl)-2-(trifluoromethyl)malonate(1455396-80-1)
• EPA Substance Registry System: (E)-dimethyl 2-(3-(p-tolyl)allyl)-2-(trifluoromethyl)malonate(1455396-80-1)

Safety Data

• Hazardous Substances Data: 1455396-80-1(Hazardous Substances Data)

Upstream product

• 3333-13-9 p-allyltoluene 
• 5838-00-6 methyl dimethyl 2-(trifluoromethyl)propanedioate 

Relevant articles and documents

Allylic C-H alkylation with a CF3-containing nucleophile

Allylic C-H alkylation of allylarenes with dimethyl 2- trifluoromethylmalonate was successfully developed. The reactions were carried out at room temperature in the presence of a catalytic amount of Pd(OAc) 2/Ph3P and a stoichiometric amount of 2,6- dimethylbenzoquinone. The reactions avoided defluorination successfully, providing a new method to construct a CF3-containing all-carbon quaternary center. The Royal Society of Chemistry 2013.